Targeted Therapy

A Double-Edged Sword in Medical Malpractice

Targeted therapy, a revolutionary approach to cancer treatment, has significantly improved patient outcomes in recent years. However, its complex nature and potential for adverse effects have also made it a focal point in medical malpractice claims. The Kopec Law Firm provides this article to better understand all aspects of targeted therapy.

A Brief History of Targeted Therapy

The concept emerged in the late 20th century, building upon advances in molecular biology. Scientists began to understand the genetic mutations that drive cancer growth, leading to the development of drugs that specifically target these abnormalities. Herceptin, approved in 1998 for the treatment of HER2-positive breast cancer, was a groundbreaking example of targeted therapy’s potential.

What is Targeted Therapy, and How Does it Work?

The drugs interfere with the molecular pathways that contribute to cancer cell growth and survival. Unlike traditional chemotherapy, which indiscriminately kills both cancer and healthy cells, this therapy aims to selectively target cancer cells while minimizing damage to normal tissues. This approach can lead to fewer side effects and improved treatment outcomes.

Medical Professionals Involved and Administration

Targeted therapy often requires a multidisciplinary team of doctors, including oncologists, pathologists, and genetic counselors. Oncologists specialize in cancer treatment and prescribe targeted therapy drugs. Pathologists analyze tissue samples to identify specific genetic mutations that may be targeted. Genetic counselors help patients understand the implications of their genetic testing results.

Targeted therapy can be administered through various routes, including oral pills, intravenous infusions, or injections. The specific method depends on the type of drug and the patient’s condition.

Types of Patients and Conditions Treated

Targeted therapy is particularly effective for patients with cancers that have specific genetic alterations. For example, patients with non-small cell lung cancer that harbors the ALK or ROS1 mutation may benefit from drugs that inhibit these proteins. Other common uses of targeted therapy include the treatment of breast cancer, colorectal cancer, and melanoma.

Effectiveness and Prognosis

While targeted therapy has shown remarkable success in certain types of cancer, its effectiveness can vary depending on the specific genetic alterations present in the tumor. Additionally, some cancers can develop resistance to this therapy over time.

The prognosis for patients treated with targeted therapy depends on various factors, including the type of cancer, the stage of the disease, and the patient’s overall health. In many cases, this therapy can significantly improve survival rates and quality of life.

Medical Malpractice Claims Involving Targeted Therapy

Despite its benefits, targeted therapy can also be a source of medical malpractice claims. Potential issues that may arise include:

• Misdiagnosis: If a patient’s genetic mutations are not accurately identified, they may not receive the most appropriate therapy.
• Failure to monitor for side effects: This therapy can have serious side effects, and healthcare providers must monitor patients closely for adverse reactions.
• Incorrect dosage: Overdosing or underdosing a drug can lead to adverse outcomes.
• Failure to consider alternative treatments: If a patient is not responding, their healthcare provider should consider other treatment options.

Medical malpractice claims can be complex, requiring a thorough understanding of the underlying science and the standard of care in oncology.

If you have any concerns or questions about treatment, then visit our free consultation page or video. Then contact the Kopec Law Firm at 800-604-0704 to speak directly with Attorney Mark Kopec. He is a top-rated Baltimore medical malpractice lawyer. The Kopec Law Firm is in Baltimore and pursues cases throughout Maryland and Washington, D.C.